Sarcopenic patients share clinical features with frailty, but just how similar are they? Researchers used metabolomic analysis to assess the metabolic profiles of sarcopenia in relation to frailty.
Aging (Aging-US) Research
Data may hold the key to cracking COVID-19. Researchers parsed through clinical data from around the world to glean new insights about this virus’ patterns.
Researchers tested antiviral, anticancer, and immunosuppressive drug combinations that may aid in treating neurodegenerative disorders, including Alzheimer’s disease.
Authors from the National Institute on Aging wrote the editorial paper, “Mitochondria as extracellular vesicle cargo in aging.”
Researchers from the Campisi Lab discovered new insights while investigating Cdkn1a transcript variants 1 and 2.
Researchers from Harvard University and the Broad Institute wrote a theory article, published by Aging in 2021, and entitled, “Shifting epigenetic contexts influence regulatory variation and disease risk.”
![Figure 1. The EORS downward spiral of aging and Alzheimer’s (Epigenetic Oxidative Redox Shift) [2]. Yellow arrows illustrate mechanistic targets that propel the vicious cycle triggered by age-related oxidative shifts (NAD+/NADH) and age-related sedentary behavior, which elicit ROS, inflammatory stress and possibly Aβ. Green arrows indicate practical interventions to decelerate the vicious cycle and impede the progression of aging and AD.](https://aging-us.org/wp-content/uploads/2021/06/Screen-Shot-2021-06-24-at-4.49.30-PM-800x600.png)
In a trending Aging editorial paper, researchers explain that switches in the aging process may be a window of opportunity for patients with Alzheimer’s disease and potential epigenetic treatments.
Is there an association between biomarkers of aging and lung function? Researchers conducted a study which aimed to find out.
Researchers surveyed available literature related to exercise and its association with longevity and aging. This extensive review expands on exercise as a lifestyle intervention and its ability to counteract cellular and tissue aging.
Researchers used a bioinformatics approach (ESHRD) that leverages gene expression data from brain tissue to derive cell-type specific alterations in Alzheimer’s disease.