Aging News & Blogs
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Gene Linked to Osteoporosis Risk in Postmenopausal Asian Women
In this recent study, researchers compared three IGF-1 polymorphisms in postmenopausal Asian women and investigated their potential link to osteoporosis.
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How Hidden Markov Models Could Elucidate Multimorbidity in Aging
In a new study, researchers investigated longitudinal multimorbidity patterns among older adults from a Swedish urban population. … continue reading
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Late-in-Life Interventions to Improve Cardiac Health
In a new research perspective, researchers discuss spermidine, rapamycin, caloric restriction, and exercise training to improve cardiac health in aging individuals. … continue reading
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New Insights Into the Mechanisms of Sarcopenia
In this new study, researchers aimed to further elucidate the mechanisms of sarcopenia by examining the influence of denervation in young and middle-aged mice. … continue reading
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Is Estrogen Dysregulation Behind Alzheimer’s Pathology?
In a new study, researchers explored Alzheimer’s disease and its potential relationship with the estrogen receptor-α gene (ESR1). … continue reading
Aging: Volume 15, Issue 2
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Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity
Type 2 diabetes is partly characterized by decreased β-cell mass and function which have been linked to cellular senescence. Despite a low basal proliferative rate of adult β-cells, they can respond to growth stimuli, but this proliferative capacity decreases with age and correlates with increased expression of senescence effector, p16Ink4a.
Insights From Authors & Announcements
Aging | Clearance of p16Ink4a+ Cells: Limited Effects on B-Cell Mass and Proliferation in MicePRESS RELEASE: A new research paper was published on the cover of Aging's Volume 15, Issue 2, entitled, “Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity.” https://doi.org/10.18632/aging.204483 The post Aging | Clearance of p16Ink4a+ Cells: Limited…
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