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Aging (Aging-US) Research

Aging (Aging-US) Research

Aging-US Research

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Aging (Aging-US) Research

Figure 1. New hallmarks of ageing.
Aging Blog News

The 2022 “New Hallmarks of Ageing” Research Symposium

September 13, 2022September 16, 2022

Researchers from Norway, Poland, Denmark, Sweden, United Kingdom, Israel, France, United States, and Taiwan authored a meeting report on the “New Hallmarks of Ageing” research symposium held in Denmark on March 22, 2022.

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Stroke Outcomes Mediated by These 2 Mechanisms
Aging Blog News Trending

Stroke Outcomes Mediated by These 2 Mechanisms

August 25, 2022September 16, 2022

In a trending new research paper published in Aging, researchers investigated the effects of microglial activity on post-stroke inflammation and outcomes.

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3 Domains of Well-Being Extend Elderly Mobility and Longevity
Aging Blog News Trending

3 Domains of Well-Being Extend Elderly Mobility and Longevity

August 18, 2022August 19, 2022

In the Volume 14, Issue 15, Aging cover paper, researchers hypothesized that multidimensional well-being may prolong mobility-limitation-free survival and longevity among older adults.

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osteoporosis
Aging Blog News

Osteoporosis Linked to Age-Related Changes in Circadian Rhythm

August 11, 2022August 12, 2022

On July 19, 2022, researchers published an editorial paper on restoring the circadian rhythm to minimize the risk of aging-related osteoporotic fractures.

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AMD
Aging Blog News Trending

Trending With Impact: Humanin G Treatment in AMD Reduces Inflammation

June 2, 2022August 2, 2022

In an Aging-US cover paper, researchers investigated a potential therapeutic intervention to reduce chronic inflammation in age-related macular degeneration (AMD).

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Neuromodulation in Alzheimer’s Disease Treatment
Aging Blog News Trending

Trending With Impact: Neuromodulation in Alzheimer’s Disease Treatment

May 26, 2022May 28, 2022

Fabrizio Vecchio wrote a new editorial paper on the potential synergistic effects of neuromodulation combined with cognitive training to treat Alzheimer’s disease.

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Hallmarks of Cancer and Aging
Aging Blog News

An Original Review on the Hallmarks of Cancer and Aging

May 19, 2022May 20, 2022

Dr. Mikhail Blagosklonny published an original review paper in Aging (Aging-US) Volume 14, Issue 9, entitled, “Hallmarks of cancer and hallmarks of aging.”

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Altos Labs
Aging Blog News

Dr. Blagosklonny’s Rapamycin-Based Recommendation for Altos Labs

May 12, 2022May 18, 2022

Mikhail Blagosklonny, M.D., Ph.D., has a recommendation for Altos Labs in his new research perspective, entitled, “Altos Labs and the quest for immortality: but can we live longer right now?”

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Figure 16. Influences of mutant and WT-TP53 on mitochondrial activity and glucose metabolism and effects of rapamycin and metformin. The effects of WT and mutant TP53 on key enzymes important in glycolysis and how they can influence metabolism and PDAC tumor growth. In our studies, we have examined the effect of GOF mutant TP53 and in some cases WT TP53. In addition, sites of interaction of the type 2 diabetes drug metformin and the immunosuppressive drug rapamycin and their effects on AMPK and mTORC1 are indicated. TP53 can induce mitochondrial apoptosis pathway by regulating the expression of PUMA and other proteins.
Aging Blog News

TP53 Restoration Sensitizes Pancreatic Cancer to Multiple Drugs

May 4, 2022May 30, 2022

In Aging’s Volume 14, Issue 8, cover paper, researchers found that the restoration of wild-type TP53 decreased pancreatic cancer cell resistance to various drugs, including rapamycin.

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Fruit flies
Aging Blog News Trending

Trending With Impact: Tobacco PEBP Increases Lifespan in Fruit Flies

April 28, 2022May 30, 2022

Researchers conducted an interspecies analysis to determine the effects on aging that occur when certain plant proteins are expressed in animals and animal proteins are expressed in plants.

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