Mitophagy is a selective form of autophagy which permits the removal of dysfunctional or excess mitochondria. This occurs as an adaptative response to physiological stressors, such as hypoxia, nutrient deprivation, or DNA damage. Mitophagy is promoted by specific mitochondrial outer membrane receptors, among which are BNIP3 and BNIP3L.
Aging (Aging-US) Research

In this new study, researchers used proteomics to investigate Werner syndrome and proteins associated with age and/or genotype in the serum and liver of mice.

In this study, researchers used a label-free liquid chromatography-tandem mass spectrometry approach to uncover proteins abundance associated with specific biological processes that differed depending on the age (four or ten months) and/or the genotype (wild type or Wrn mutant) in the serum and liver of mice.

According to birth certificates, the life of a child begins once their body comes out of the mother’s womb. But when does their organismal life begin? Science holds a palette of answers—depending on how one defines a human life.