According to birth certificates, the life of a child begins once their body comes out of the mother’s womb. But when does their organismal life begin? Science holds a palette of answers—depending on how one defines a human life.
Aging (Aging-US) Research

In this new study, researchers investigated the senescent phenotypes of human corneal endothelial cells upon UV-A exposure.

Purpose: The objective of this study was to investigate the senescent phenotypes of human corneal endothelial cells (hCEnCs) upon treatment with ultraviolet (UV)-A.

In this new study, researchers provide the first evidence of a pan-tissue decrease of stemness during human aging.

Despite their biological importance, the role of stem cells in human aging remains to be elucidated. In this work, researchers applied a machine learning methodology to GTEx transcriptome data and assigned stemness scores to 17,382 healthy samples from 30 human tissues aged between 20 and 79 years…