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Aging (Aging-US) Research

Aging (Aging-US) Research

Aging-US Research

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Aging (Aging-US) Research

Volume 16, Issue 6
Aging Latest Issue

Altered brain morphology and functional connectivity in postmenopausal women: automatic segmentation of whole-brain and thalamic subnuclei and resting-state fMRI

April 1, 2024

The purpose of this study was not only to compare the brain volume changes between premenopausal and postmenopausal women, but also to evaluate the functional connectivity between the targeted brain regions associated with structural atrophy in postmenopausal women.

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Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging
Aging Latest Issue

Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging

April 1, 2024April 1, 2024
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CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction
Aging Latest Issue

CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction

April 1, 2024April 1, 2024
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Predicting Brain Age With Machine Learning and Transcriptome Profiling
Aging Blog News

Predicting Brain Age With Machine Learning and Transcriptome Profiling

March 21, 2024

In this study, researchers investigated age-associated gene expression changes in the prefrontal cortex of male and female brains and used machine learning to develop age prediction models.

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Volume 16, Issue 5
Aging Latest Issue

Genome-wide transcriptome profiling and development of age prediction models in the human brain

March 15, 2024

Aging-related transcriptome changes in various regions of the healthy human brain have been explored in previous works, however, a study to develop prediction models for age based on the expression levels of specific panels of transcripts is lacking…

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FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet
Aging Latest Issue

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet

March 15, 2024
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PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation
Aging Latest Issue

PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation

March 15, 2024
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Overcoming Missing Data in the Swedish National Study on Aging
Aging Blog News

Overcoming Missing Data in the Swedish National Study on Aging

March 7, 2024

In this new study, researchers compared three multiple imputation strategies for overcoming the missing discrete variable of gait speed in the Swedish National Study on Aging and Care (SNAC).

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Volume 16, Issue 4
Aging Latest Issue

Mapping the core senescence phenotype of primary human colon fibroblasts

February 29, 2024

Advanced age is the largest risk factor for many diseases and several types of cancer, including colorectal cancer (CRC). Senescent cells are known to accumulate with age in various tissues, where they can modulate the surrounding tissue microenvironment through their senescence associated secretory phenotype (SASP).

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Multiple imputation of systematically missing data on gait speed in the Swedish National Study on Aging and Care
Aging Latest Issue

Multiple imputation of systematically missing data on gait speed in the Swedish National Study on Aging and Care

February 29, 2024
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