The impact of the senescence related microenvironment on cancer prognosis and therapeutic response remains poorly understood. In this study, researchers investigated the prognostic significance of senescence related tumor microenvironment genes (PSTGs) and their potential implications for immunotherapy response…

Observational studies in preclinical models demonstrate age-related declines in circadian functions. The researchers hypothesized that age would be associated with declines in function of cell-autonomous circadian clocks in human tissue.

In the current study, researchers investigated the neural mechanisms serving working memory (WM) function in seventy-eight healthy aging adults (range: 20.2–65.2 years) using magnetoencephalography (MEG) and a Sternberg WM task with letter stimuli.