In this study, researchers used a variety of target identification and prioritization techniques offered by the AI-powered PandaOmics platform, to propose a list of promising novel aging-associated targets that may be used for drug discovery.
Aging (Aging-US) Research
Mucins are components of the mucus layer overlying the intestinal epithelial cells, which maintains physiological homeostasis. Altered mucin expression is associated with disease progression. Expression of MUC4 decreases in colorectal cancer (CRC); however, its functional role and implications in the intestinal pathology in CRC are not studied well…
In this cohort study involving 1,676 healthy participants (mean age 40) with up to 15 years of follow up, researchers evaluated the associations between cognitive function and two classes of novel biological aging markers: blood-based epigenetic aging and neuroimaging-based brain aging.
Authors hypothesize that radiation-induced senescent parenchymal cells in irradiated lung would enhance tumor growth.