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Aging (Aging-US) Research

Aging (Aging-US) Research

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Aging (Aging-US) Research

Replicative Senescence
Aging Blog News Trending

Trending With Impact: Underlying Mechanisms of Replicative Senescence

April 21, 2022April 26, 2022

Published on the cover of Aging’s Volume 14, Issue 7, researchers conducted a new study investigating the role of IGFBP5 in replicative senescence.

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Volume 14, Issue 7
Aging Latest Issue

Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts

April 15, 2022

Insulin-like growth factor (IGF)-binding proteins (IGFBPs) are secretory proteins that regulate IGF signaling. In this study, the researchers investigated the role of IGFBP5 in replicative senescence in embryonic mouse fibroblasts (MEFs).

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Figure 1. Flowchart of the analyzed subjects.
Aging Latest Issue

Association between sleep parameters and longitudinal shortening of telomere length

April 15, 2022April 15, 2022
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Figure 1. Modeling the combined impact of heterozygous E-cadherin loss and aging on the murine prostate.
Aging Latest Issue

E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice

April 15, 2022April 15, 2022
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Immunofluorescence detection of GRSF1 (green) and mitochondria (red) in proliferating myoblasts and differentiating myotubes. Arrowheads indicate GRSF1 signals; n=3. Scale bar, 50 μm.
Aging Blog News

Protein Linked to Aging-Related Muscle Loss

April 13, 2022September 16, 2022

Researchers investigated the mitochondrial protein GRSF1 for its role in the physiology of skeletal muscle aging.

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IVF
Aging News Trending

Trending With Impact: Plasma Injection Improves Poor Response to IVF

April 7, 2022April 20, 2022

Researchers investigated the effects of injecting platelet-rich plasma in women with a poor ovarian response to in vitro fertilization (IVF).

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Volume 14, Issue 6
Aging Latest Issue

Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine

March 31, 2022March 31, 2022

In this study, researchers used a variety of target identification and prioritization techniques offered by the AI-powered PandaOmics platform, to propose a list of promising novel aging-associated targets that may be used for drug discovery.

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Regulation of mTOR complexes in long-lived growth hormone receptor knockout and Snell dwarf mice
Aging Latest Issue

Regulation of mTOR complexes in long-lived growth hormone receptor knockout and Snell dwarf mice

March 31, 2022March 31, 2022
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Association between social isolation and reduced mental well-being in Swedish older adults during the first wave of the COVID-19 pandemic: the role of cardiometabolic diseases
Aging Latest Issue

Association between social isolation and reduced mental well-being in Swedish older adults during the first wave of the COVID-19 pandemic: the role of cardiometabolic diseases

March 31, 2022March 31, 2022
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PandaOmics Identifies Duel-Targets of Aging and Age-Related Diseases
Aging Blog News Trending

PandaOmics Identifies Dual-Targets of Aging and Age-Related Diseases

March 31, 2022April 20, 2022

Researchers used PandaOmics software to identify potential drug targets that could treat both aging and age-related diseases.

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