Skip to content
Aging (Aging-US) Research

Aging (Aging-US) Research

Aging-US Research

  • Facebook
  • Twitter
  • Instagram
  • LinkedIn
  • YouTube
  • Pinterest
  • SoundCloud
  • Reddit
  • Home
  • News

Aging (Aging-US) Research

Volume 14, Issue 10
Aging Latest Issue

Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)

May 31, 2022May 31, 2022

Inflammation plays a crucial role in the etiology and pathogenesis of AMD (Age-related Macular Degeneration). Humanin G (HNG) is a Mitochondrial Derived Peptide (MDP) that is cytoprotective in AMD and can protect against mitochondrial and cellular stress induced by damaged AMD mitochondria…

Read More
Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence
Aging Latest Issue

Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence

May 31, 2022May 31, 2022
Read More
Aging-US.org
Aging Latest Issue

The roles of inactivated vaccines in older patients with infection of Delta variant in Nanjing, China

May 31, 2022May 31, 2022
Read More
Neuromodulation in Alzheimer’s Disease Treatment
Aging Blog News Trending

Trending With Impact: Neuromodulation in Alzheimer’s Disease Treatment

May 26, 2022May 28, 2022

Fabrizio Vecchio wrote a new editorial paper on the potential synergistic effects of neuromodulation combined with cognitive training to treat Alzheimer’s disease.

Read More
Hallmarks of Cancer and Aging
Aging Blog News

An Original Review on the Hallmarks of Cancer and Aging

May 19, 2022May 20, 2022

Dr. Mikhail Blagosklonny published an original review paper in Aging (Aging-US) Volume 14, Issue 9, entitled, “Hallmarks of cancer and hallmarks of aging.”

Read More
Volume 14, Issue 9
Aging Latest Issue

Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin

May 15, 2022May 15, 2022

Naked mole-rats (NMR) are subterranean rodents characterized by an unusual longevity coupled with an unexplained resistance to aging. In the present study, we performed extensive in situ analysis and single-cell RNA-sequencing comparing young and older animals…

Read More
miRNAs-mediated overexpression of Periostin is correlated with poor prognosis and immune infiltration in lung squamous cell carcinoma
Aging Latest Issue

miRNAs-mediated overexpression of Periostin is correlated with poor prognosis and immune infiltration in lung squamous cell carcinoma

May 15, 2022May 15, 2022
Read More
Transcriptional expressions of hsa-mir-183 predicted target genes as independent indicators for prognosis in bladder urothelial carcinoma
Aging Latest Issue

Transcriptional expressions of hsa-mir-183 predicted target genes as independent indicators for prognosis in bladder urothelial carcinoma

May 15, 2022May 15, 2022
Read More
Altos Labs
Aging Blog News

Dr. Blagosklonny’s Rapamycin-Based Recommendation for Altos Labs

May 12, 2022May 18, 2022

Mikhail Blagosklonny, M.D., Ph.D., has a recommendation for Altos Labs in his new research perspective, entitled, “Altos Labs and the quest for immortality: but can we live longer right now?”

Read More
Figure 16. Influences of mutant and WT-TP53 on mitochondrial activity and glucose metabolism and effects of rapamycin and metformin. The effects of WT and mutant TP53 on key enzymes important in glycolysis and how they can influence metabolism and PDAC tumor growth. In our studies, we have examined the effect of GOF mutant TP53 and in some cases WT TP53. In addition, sites of interaction of the type 2 diabetes drug metformin and the immunosuppressive drug rapamycin and their effects on AMPK and mTORC1 are indicated. TP53 can induce mitochondrial apoptosis pathway by regulating the expression of PUMA and other proteins.
Aging Blog News

TP53 Restoration Sensitizes Pancreatic Cancer to Multiple Drugs

May 4, 2022May 30, 2022

In Aging’s Volume 14, Issue 8, cover paper, researchers found that the restoration of wild-type TP53 decreased pancreatic cancer cell resistance to various drugs, including rapamycin.

Read More

Posts pagination

Previous 1 … 27 28 29 … 35 Next
  • twitter

Copyright © 2023 Impact Journals, LLC

Impact Journals is a registered trademark of Impact Journals, LLC