A new study compared circulating miRNAs and their association with cognitive function and decline among cognitively “normal” men.
Aging (Aging-US) Research
Background: Aging-related cognitive decline is an early symptom of Alzheimer’s disease and other dementias, and on its own can have substantial consequences on an individual’s ability to perform important everyday functions…
Researchers from Norway, Poland, Denmark, Sweden, United Kingdom, Israel, France, United States, and Taiwan authored a meeting report on the “New Hallmarks of Ageing” research symposium held in Denmark on March 22, 2022.
Accumulation of senescent cells in tissues with advancing age participates in the pathogenesis of several human age-associated diseases. Specific senescent secretome, the resistance of senescent cells to apoptotic stimuli, and lack of immune system response contribute to the accumulation of senescent cells and their adverse effects in tissues…
![Figure 1. Risk of mortality and morbidity associated with serum IGF-1 levels, stratified by age groups [5].](https://aging-us.org/wp-content/uploads/2022/08/Screen-Shot-2022-08-31-at-4.14.07-PM.png)
The role of insulin-like growth factor 1 (IGF-1) in human aging has been hotly debated.
Background: While iron is essential for normal brain functioning, elevated concentrations are commonly found in neurodegenerative diseases and are associated with impaired cognition and neurological deficits.
