Aging (Aging-US) Research
In a new study, researchers investigated the effectiveness and safety of EGFR-tyrosine kinase inhibitors in elderly patients with EGFR-mutated advanced non-small-cell lung cancer (NSCLC).
Observational studies in preclinical models demonstrate age-related declines in circadian functions. The researchers hypothesized that age would be associated with declines in function of cell-autonomous circadian clocks in human tissue.
In the current study, researchers investigated the neural mechanisms serving working memory (WM) function in seventy-eight healthy aging adults (range: 20.2–65.2 years) using magnetoencephalography (MEG) and a Sternberg WM task with letter stimuli.
In a new editorial, researchers discuss interconnected mechanisms of neuronal functionality and available tools to investigate neuronal aging and longevity.