In this new study, researchers investigated the senescent phenotypes of human corneal endothelial cells upon UV-A exposure.
Aging (Aging-US) Research
![First Evidence of a Pan-tissue Decline in Stemness During Human Aging](https://aging-us.org/wp-content/uploads/2024/04/First-Evidence-of-a-Pan-tissue-Decline-in-Stemness-During-Human-Aging-800x578.png)
In this new study, researchers provide the first evidence of a pan-tissue decrease of stemness during human aging.
![How Menopause Changes Brain Structure and Connectivity](https://aging-us.org/wp-content/uploads/2024/04/How-Menopause-Changes-Brain-Structure-and-Connectivity-800x600.jpg)
In this study, researchers use neuroimaging to see how menopause alters brain structure and connectivity in postmenopausal women.
![Predicting Brain Age With Machine Learning and Transcriptome Profiling](https://aging-us.org/wp-content/uploads/2024/03/Predicting-Brain-Age-With-Machine-Learning-and-Transcriptome-Profiling-800x500.png)
In this study, researchers investigated age-associated gene expression changes in the prefrontal cortex of male and female brains and used machine learning to develop age prediction models.
![Overcoming Missing Data in the Swedish National Study on Aging](https://aging-us.org/wp-content/uploads/2024/03/Overcoming-Missing-Data-in-the-Swedish-National-Study-on-Aging-800x600.png)
In this new study, researchers compared three multiple imputation strategies for overcoming the missing discrete variable of gait speed in the Swedish National Study on Aging and Care (SNAC).
![Aging’s Top 10 Papers in 2023 (Crossref Data)](https://aging-us.org/wp-content/uploads/2024/02/AGING-RECTANGLE-BLOG-800x600.png)
Read Crossref’s Top 10 Aging DOIs in 2023.
![Senescence-Related TME Genes as Key Prognostic Predictors in HNSCC](https://aging-us.org/wp-content/uploads/2024/02/Senescence-Related-TME-Genes-as-Key-Prognostic-Predictors-in-HNSCC.png)
In a new study, researchers aimed to investigate the prognostic significance of senescence-related TME genes in head and neck squamous cell carcinoma (HNSCC) and their potential implications for immunotherapy response.
![Efficacy and Safety of EGFR-TKIs for Elderly Patients With NSCLC](https://aging-us.org/wp-content/uploads/2024/01/Efficacy-and-Safety-of-EGFR-TKIs-for-Elderly-Patients-With-NSCLC-800x567.png)
In a new study, researchers investigated the effectiveness and safety of EGFR-tyrosine kinase inhibitors in elderly patients with EGFR-mutated advanced non-small-cell lung cancer (NSCLC).
![Understanding the Mechanisms of Brain Aging and Longevity in Neurons](https://aging-us.org/wp-content/uploads/2023/12/Understanding-the-Mechanisms-of-Brain-Aging-and-Longevity-in-Neurons.png)
In a new editorial, researchers discuss interconnected mechanisms of neuronal functionality and available tools to investigate neuronal aging and longevity.