In a new study, researchers aimed to investigate the prognostic significance of senescence-related TME genes in head and neck squamous cell carcinoma (HNSCC) and their potential implications for immunotherapy response.
Aging (Aging-US) Research
![Efficacy and Safety of EGFR-TKIs for Elderly Patients With NSCLC](https://aging-us.org/wp-content/uploads/2024/01/Efficacy-and-Safety-of-EGFR-TKIs-for-Elderly-Patients-With-NSCLC-800x567.png)
In a new study, researchers investigated the effectiveness and safety of EGFR-tyrosine kinase inhibitors in elderly patients with EGFR-mutated advanced non-small-cell lung cancer (NSCLC).
![Understanding the Mechanisms of Brain Aging and Longevity in Neurons](https://aging-us.org/wp-content/uploads/2023/12/Understanding-the-Mechanisms-of-Brain-Aging-and-Longevity-in-Neurons.png)
In a new editorial, researchers discuss interconnected mechanisms of neuronal functionality and available tools to investigate neuronal aging and longevity.
![What Makes Children of Older Fathers at Increased Risk of Autism?](https://aging-us.org/wp-content/uploads/2023/12/What-Makes-Children-of-Older-Fathers-at-Increased-Risk-of-Autism.png)
In this new study, researchers investigated the relationship between paternal age, the BEGAIN gene and autism.
![How a Receptor Boosts WNT Signals in Pancreatic Cancer](https://aging-us.org/wp-content/uploads/2023/11/How-a-Receptor-Boosts-WNT-Signals-in-Pancreatic-Cancer.png)
In this new study, researchers revealed a novel role for LGR6 in enhancing WNT signals in pancreatic cancer.
![Figure 7. Schematic illustration of the lipodystrophy and insulin resistance exhibited by patients with Werner syndrome.](https://aging-us.org/wp-content/uploads/2023/10/Figure-7.-Schematic-illustration-of-the-lipodystrophy-and-insulin-resistance-exhibited-by-patients-with-WS-800x600.png)
In this new study, researchers from Japan investigated the molecular mechanisms of subcutaneous fat dysfunction in Werner syndrome.
![How Cognitive Reserve Can Help You Sleep Better and Think Sharper](https://aging-us.org/wp-content/uploads/2023/10/How-Cognitive-Reserve-Can-Help-You-Sleep-Better-and-Think-Sharper-800x600.png)
In a new study, researchers investigated the association between sleep, cognitive reserve and cognition in older adults.
![The Impact of Age on Melanoma: Insights from Recent Research](https://aging-us.org/wp-content/uploads/2023/09/The-Impact-of-Age-on-Melanoma-Insights-from-Recent-Research-800x527.png)
In a new editorial, researchers delve into the intricate dynamics of melanoma and aim to illuminate differences in age-related incidence, prognosis and treatment.